I've used the Seagate Momentus XT hybrid drives in most of my laptops before and I *do* notice a speedier difference. The hybrids normally have a small amount of SSD space (4GB or so) and it is used for caching repetitive data. So for example, if you reboot your machine a lot, it will notice this and start caching the startup files. Next time you reboot, the bootup process will be much faster. Local applications are similar so that if you always open up Excel it will make it a bit faster.
For the price ($90 for 500GB sometimes), space and the increase in performance, I'd say these are a good stepping point before moving over to a full SSD as your primary drive.
Lobo