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Chemical stops some of the crap associated with drunkening

deep

TRIBE Member
How Drug Binds To Neurons To Stop Drunken Symptoms Of Alcohol

UCLA researchers discovered how an experimental drug, called Ro15-4513, binds to specific receptors on brain neurons, which helps explain how this drug stops the drunken behavioral symptoms of alcohol such as impaired motor coordination, memory loss and drowsiness.

The team showed in the lab that Ro15-4513 binds to and blocks alcohol action on these highly alcohol-sensitive receptors. The UCLA group previously found that these receptors are specific subtypes of Gamma-amino butyric acid (GABA-A) receptors that play a role in impairing motor coordination caused by alcohol in experimental animals.

These studies are the first to show how the alcohol antidote drug Ro15-4513 binds to these GABA-A receptors. The research may lead to a better understanding of how alcohol works in the brain as well as help develop drugs that prevent alcohol actions such as a sober-up pill, and alcohol addiction medications and treatments.UCLA researchers also suggest in the future that it may be possible to harness the beneficial effects of alcohol on the body, including inducing sleep, enhancing mood or mirroring the positive effects of moderate alcohol consumption on the heart and brain.

Authors of the study include Richard W. Olsen, Ph.D., professor and Martin Wallner, Ph.D., researcher, both in the UCLA Department of Molecular and Medical Pharmacology. The research appears in the May 8 online edition of the Proceedings of the National Academy of Sciences.

The study was funded by the National Institutes of Health, the Alcoholic Beverage Medical Research Foundation, and the State of California for medical research on alcohol and substance abuse.
http://www.sciencedaily.com/releases/2006/05/060510192138.htm
 
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Funzo

TRIBE Member
Finally. I can go out and get shitface, rail some of this after the bar, and be on my way to driving home.

No fuss, no muss!
 

Jeffsus

TRIBE Member
This has serious ramifications for my general well being.

*Sits down very deepy, in my plush, wide, leather chair....*

-jM
A&D
 

grumblegirl

TRIBE Member
all i care about is when will they come out with a pill that helps us sad souls who can't digest alcohol properly... i mean - they have one for milk now... what's more important, really? being able to drink from the teat of a cow, or being able to get really really krunk?
 

djdeposit

TRIBE Member
in other news researchers have found that a pill developed to block drunken receptors has been changing the sex of people.
 

quantumize

TRIBE Member
wow this thng would change the entire dynamic of tribe as we know it


also it would make sex between ugly people a near impossibility
 
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Jeffsus

TRIBE Member
They don't need a pill to cure drunkenness. They need a pill to cure hangovers. That's where the REAL money is.

-jM
A&D
 

basketballjones

TRIBE Member
Jeffsus said:
They don't need a pill to cure drunkenness. They need a pill to cure hangovers. That's where the REAL money is.

-jM
A&D
they have some good stuff for that in the UK, it is called Resolve, it is chock full of amphetamines and such....but it only works for about an hour, but even still
try to drink a buttload of water b4 you go to bed and sleep for at least 10 hours, the first 6 are just your body burning off the booze
not like i know anything about this cause i am a tea-tottler
 

Rude1_247

TRIBE Member
Depending on who you ask on this board, I'm sure quite a few would have thought this was old news..... although they probably would have laughed when you told them it was Ro15-4513 and informed you that it was spelled "b-l-o-w".
 

Dr Funk MD

TRIBE Promoter
Funzo said:
Finally. I can go out and get shitface, rail some of this after the bar, and be on my way to driving home.

No fuss, no muss!
I know you're just joking but it brinkgs up a valid point. You might not feel drunk but has your reation time been improved as well? And you'd still blow over the limit on a breathalizer test.
 
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defazman

TRIBE Member
that's right, make sure to tell Jeffsus how to deal with booze.

now between this, viagra and roofies my weekend is complete.
 
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