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Cannabis MS drug 'available soon'

exheres

TRIBE Member
Cannabis MS drug 'available soon'
Wednesday, January 21, 2004 Posted: 1354 GMT ( 9:54 PM HKT)

LONDON, England (CNN) -- A cannabis-based medicine for multiple sclerosis sufferers could be available on prescription in Britain by the summer, according to its manufacturer.

UK-based GW Pharmaceuticals said production and marketing teams were on stand-by to launch Sativex, subject to it gaining regulatory approval.

The firm said its application was close to winning approval from the UK Medicines and Healthcare Regulatory Agency.

Executive chairman Dr. Geoffrey Guy said: "We have every reason to be extremely excited about the year ahead."

The group hopes the assessment process will be finished during the second quarter of 2004 and that the product will be available on prescription soon afterwards.

GW Pharmaceuticals, which floated on the London Stock Exchange in 2002, is the only company to legally develop and produce cannabis-derived treatments.

Anecdotal evidence suggests that more than 10 percent of multiple sclerosis sufferers use cannabis illegally to help alleviate their symptoms of pain, muscle spasm and shaking.

GW Pharmaceuticals has developed three means of administering the drug. The first is by spraying it in the mouth, another is by taking a pill and the third is by vaporizer -- rather like an asthma inhaler.

Richard Payne is one of the patients who took part in the clinical trials. He was diagnosed with MS in 1985.

And although there is no cure for the disease which attacks the central nervous system, he found his quality of life was dramatically improved.

"My sleeping patterns were very disrupted through spasms and twitching and bladder problems. They were the main areas which I was concerned about which were causing problems," Payne told CNN.

"Having taken cannabis it has helped those areas -- so now I have found a level that suits me. My bladder problems are much better and my quality of life much better."

However, experts caution that cannabis is not a cure-all.

"It does need to be treated with caution," according to Marianne Miles, director of the MS Society.

"But as well as a cure it is important that we look at drugs that will affect the quality of life of people with MS.

"For someone who has pain or spasticity if that can be relieved then many people say they can live with their MS as a disease -- if they can get rid of some of the symptoms that go with the condition."

Because of its cannabis content, Sativex will require a change in the law, which UK ministers have already said they will recommend.

Once GW Pharmaceuticals has won approval from British regulators it will start the process elsewhere in Europe and in North America.
~~~~~~~~~~~~~~~~~~~~~~


:D there goes the mj debate.
actually i found this pretty funny.
 
Cannabis Seed Wedding Bands

patri©k

TRIBE Member
Sativex. what a ghey name. cannabis and synthetic cannabidiol have also been used successfully to treat glaucoma, arthritis, depression and mood disorders, migraines and chronic pain.


:cool:
 

Lysistrata

Well-Known TRIBEr
There already is one here, it's called Marinol:

Brand Name
Marinol

Common Name
dronabinol

How does this medication work? What will it do for me?
Dronabinol is a member of the family of drugs known as cannabinoids. Dronabinol is also known as THC (delta-9-tetrahydrocannabinol). This medication was developed after it was discovered that the THC found in marijuana was effective in preventing severe nausea and vomiting associated with cancer chemotherapy. This medication is used only after it is found that other medications used for the treatment of nausea and vomiting of chemotherapy have been tried and found ineffective. Your doctor may choose to use this medication for other conditions not listed here. If you're unsure why you are taking this medication, contact your doctor.



How should I use this medication?

The recommended adult dose of dronabinol is based on body surface area, which is based on height and weight. For example, a 115 cm tall child weighing 35 kg would have a body surface area of 1.0 metres squared (m2). The normal initial dose of dronabinol is 5 mg per m2 given one to three hours before chemotherapy. This dose can be repeated every two to four hours following chemotherapy, when necessary, for a total of not more than 4 to 6 doses in one day, usually for one or two days.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a different dose than the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double up on doses. Dronabinol should be stored away from children in a cool place, in a well-sealed amber-coloured container (to protect against light).



What form(s) does this medication come in?

Dronabinol is available as a white 2.5 mg capsule, a brown 5 mg capsule, and an orange 10 mg capsule. Nonmedicinal ingredients include methylparaben, propylparaben, gelatin, glycerin, sesame oil, titanium dioxide, and purified water. The 5 mg and 10 mg capsules contain FD&C Yellow No. 6, and the 5 mg capsule also contains FD&C Blue No. 1 and Red No. 40.This product does not contain starch, lactose, yeast, or gluten.



Who should NOT take this medication?

Dronabinol should not be used by people who:

are allergic to any of the ingredients, notably sesame oil
are allergic to marijuana
have a history of psychotic disorders
are judged to be intolerant of the drug


What side effects are possible with this medication?

The following side effects may go away as your body becomes used to the medicine. Check with your doctor if the following side effects continue or become bothersome.

Common

clumsiness or unsteadiness
dizziness
drowsiness
false sense of well-being
nausea
trouble thinking
vomiting
Less common or rare

blurred vision or any changes in vision
dryness of mouth
feeling faint or lightheaded, especially when getting up from a lying or sitting position
flushing of face
restlessness
unusual tiredness or weakness
Call your doctor as soon as possible if any of the following side effects occur:

Less common or rare

amnesia (memory loss)
changes in mood
confusion
delusions
feelings of unreality
hallucinations
mental depression
nervousness or anxiety
fast or pounding heartbeat
The signs of overdose include the following:

being forgetful
change in sense of smell, taste, sight, sound or touch
change in how fast you think time is passing
constipation
ecrease in coordination
severe drowsiness
severe dryness of mouth
false sense of well-
fast or pounding heartbeat
feeling dizzy or lightheaded, especially when getting up from lying or sitting
feeling sluggish
mood changes
panic reaction
problems in urinating
redness of eyes
seizures
slurred speech
unusual drowsiness or dullness
Other side effects not listed above may occur in some people. If you notice any other effects, check with your doctor.



Are there any other precautions or warnings for this medication?

Occupational hazards: You should not drive or engage in activities requiring unimpaired judgment and coordination while using this medication.

Pregnancy: The safety of dronabinol for use during pregnancy has not been established. This drug should be used in pregnancy only if the expected benefits outweigh the potential risks.

Breast-feeding: Dronabinol is excreted in breast milk and may be absorbed by the nursing baby. Nursing mothers should not use dronabinol.

Heart disease: Dronabinol should be used with caution by people with high blood pressure, angina, or abnormal heart rhythms, as it can affect these conditions adversely.



What other drugs could interact with this medication?

The following medications may be affected by dronabinol or affect how dronabinol works:

drugs that cause drowsiness such as tranquilizers, barbiturates, sleeping aids, alcohol
tricyclic antidepressants (e.g., amitriptyline, desipramine)
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

stop taking one of the medications,
change one of the medications to another,
change how you are taking one or both of the medications, or
leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, decongestants, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

from www.medbroadcast.com
 
tribe cannabis accessories silver grinders

patri©k

TRIBE Member
You should read the book by Dr Lester Grinspoon and James Bakalar entitled, "Marihuana: The Forbidden Medicine"

Yale University Press, New Haven and London, 1993.

very interesting.


smokeyp
 
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